Description
KPV Peptide (Oral Formulation) – For Research Use Only
Chemical Profile
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Name: KPV (Lys-Pro-Val)
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Sequence: Lysine–Proline–Valine (tripeptide)
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Molecular Formula: C₁₅H₂₈N₆O₄
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CAS Number: 3640-58-8
Mechanism & Research Applications
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KPV is a bioactive tripeptide derived from the alpha-melanocyte stimulating hormone (α-MSH) with anti-inflammatory and immunomodulatory properties demonstrated in vitro and in vivo.
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Investigated for potential therapeutic effects in inflammatory bowel disease, dermatitis, and other inflammatory conditions via modulation of macrophage activity and cytokine release.
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Oral delivery research is ongoing; peptide stability and absorption in the GI tract remain under study.
Oral Bioavailability & Administration
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Oral bioavailability is limited due to enzymatic degradation in the digestive system.
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Formulations often include protective delivery systems (e.g., enteric coatings) to enhance stability and absorption in research models.
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Dosing in animal studies varies widely; no established human dosing or clinical approval exists.
Safety & Regulatory Status
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KPV is not FDA-approved for human or veterinary use.
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Supplied exclusively for laboratory research and must be clearly labeled:
“For research use only. Not for human or veterinary use.”
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Safety profile in humans is not fully characterized; use caution in handling and administration.

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